Choroidal structural changes correlate with severity of diabetic retinopathy in diabetes mellitus

BMC Ophthalmology

Table 2 OCT parameters between healthy controls and diabetes group

	Control	DM	P value
Number of eyes (n)	38	66
RNFL thickness (um), median (IQR)	11 (10,12.25)	11 (10,13)	P = 0.407^#
Retinal thickness (um), mean ± SD	240.58 ± 20.64	238.85 ± 15.33	P = 0.654^*
CT (um), mean ± SD
Subfoveal	212.63 ± 11.99	213.21 ± 19.02	P = 0.849^*
Nasal	233.03 ± 16.69	234.05 ± 19.57	P = 0.788^*
Temporal	216.95 ± 19.32	219.71 ± 20.61	P = 0.502^*
Choroid vascular parameters
TCA in mm², mean ± SD	0.81 ± 0.14	0.85 ± 0.08	P = 0.086^*
LA in mm², mean ± SD	0.54 ± 0.09	0.54 ± 0.07	P = 0.825^*
SA in mm², mean ± SD	0.26 ± 0.07	0.31 ± 0.04	P < 0.001^*,†
L/C ratio	0.68 ± 0.06	0.63 ± 0.04	P < 0.001^*,†

OCT, optical coherence tomography; IQR, interquartile range; SD, standard deviation; CT, choroidal thickness; TCA, total choroidal area; LA, luminal area; SA, stromal area; L/C ratio, the ratio of the luminal to choroidal area
*: P values were calculated using the Independent t-test
#: P values were calculated using the Mann-Whitney U test
†: Significant difference between mean values of control eyes and DM eyes

ISSN: 1471-2415