Choroidal structural changes correlate with severity of diabetic retinopathy in diabetes mellitus

BMC Ophthalmology

Table 3 Choroidal parameters of all the patients

	No DR eyes	PRP-untreated NPDR eyes	PRP-untreated PDR eyes	P value
Number of eyes (n)	22	24	20
SCT (um), mean ± SD	194.18 ± 5.68	217.29 ± 14.07	229.25 ± 13.89	P < 0.001^*,†,‡,§
Choroid vascular parameters, mean ± SD
TCA in mm²	0.81 ± 0.06	0.86 ± 0.09	0.90 ± 0.08	P < 0.001^*,†,‡
LA in mm²	0.53 ± 0.05	0.54 ± 0.08	0.55 ± 0.08	P = 0.507^*
SA in mm²	0.28 ± 0.03	0.31 ± 0.05	0.34 ± 0.03	P < 0.001^*,†,‡
L/C ratio	0.65 ± 0.03	0.63 ± 0.05	0.61 ± 0.04	P = 0.019^*,†,‡,§

DR, diabetic retinopathy; PRP, panretinal photocoagulation; NPDR, non-proliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; SCT, subfoveal choroidal thickness; SD, standard deviation; TCA, total choroidal area; LA, luminal area; SA, stromal area; L/C ratio, the ratio of the luminal to choroidal area
*: Statistical significance tested by ANOVA for normal distributions and Kruskal–Wallis tests for nonnormal distributions; all comparisons were corrected with the post hoc test
†: Significant difference between mean values of DM with no DR eyes and PRP-untreated NPDR eyes
‡: Significant difference between mean values of DM with no DR eyes and PRP-untreated PDR eyes
§: Significant difference between mean values of PRP-untreated NPDR eyes and PRP-untreated PDR eyes

ISSN: 1471-2415