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Table 2 International Clinical Diabetic Retinopathy Disease Severity Scale, American Academy of Ophtalmology

From: Serum erythropoietin concentration and its correlation with stage of diabetic retinopathy

Proposed Disease Severity Level

Finding Observable upon Dilated Ophtalmoscopy

DM, without DR

No abnormalities

Non-proliferative DR

Mild

Microaneurysms only

Moderate

Microaneurysms, exudate, venous beading, IRMA

Severe

More than 20 intraretinal hemorrhages in each of 4 quadrants, definite venous beading in 2+ quadrants, prominent IRMA and 1+ quadrant; and no signs of proliferative retinopathy (4:2:1 rule)

Proliferative DR

Mild

Neovascularization

Vitreous/preretinal hemorrhage

Moderate

Severe

- High-risk

- Advanced