Fig. 2
From: Novel mutations of RPGR in Chinese families with X-linked retinitis pigmentosa
Family 2 with a novel nonsense mutation c.2833G > T(p. E945X) in ORF15 of the RPGR gene. a The pedigree of family 2. Filled squares represent to affected patients, unfilled squares or circles represent unaffected individuals, and dotted circles represent carriers. Squares represent males, and circles represent females. Arrow refers to the proband. M marks the mutant allele, and + marks the normal allele. b, c The 30-year-old proband’s (IV:5) fundus photographs showing pallor of the disc, attenuated blood vessels and tapetal-like fundus change. d The left graph represents a normal sequence chromatogram, the middle graph represents a female carrier’s sequence chromatogram and the right graph represents a male patient’s sequence chromatogram