Safety and efficacy of a standardized intracameral combination of mydriatics and anesthetic for cataract surgery in type-2 diabetic patients

Table 3 Change in endothelial cell density from preoperatively to 1 month postoperatively (Safety set)

	Diabetics		Non-Diabetics
	ICMA Group (N = 16)	Topical Group (N = 12)	ICMA Group (N = 150)	Topical Group (N = 156)
Preoperative Endothelial Cell Density (cells/mm²)
Mean ± SD	2262.1 ± 396.3	2345.9 ± 283.5	2400.1 + 420.6	2401.9 ± 415.3
Min – Max	1330–2813	1970–2943	1498–3692	974–3662
Change in Endothelial Cell Density at 1 month post-surgery (cells/mm²)
Mean ± SD	− 163.4 ± 347.5	− 121.3 ± 412.0	− 224.8 ± 417.3	− 185.2 ± 388.6
(%)	(−7.2)	(− 5.2)	(− 9.4)	(− 7.7)
Min – Max	− 955 – 526	− 749 – 708	− 1843 – 976	− 2076 – 600

A decrease in endothelial cell counts is indicated by negative numbers; ICMA Group = patients who received an intracameral injection of a standardized combination of 1% lidocaine, 0.02% tropicamide, and 0.31% phenylephrine immediately after the 1st corneal incision. Topical Group = patients who received a topical regimen of 1 drop each of 10% phenylephrine and 0.5% tropicamide

ISSN: 1471-2415