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Table 1 Median of slit lamp examination score in the rabbit bacterial keratitis model

From: Contribution of anti-inflammatory and anti-virulence effects of azithromycin in the treatment of experimental Staphylococcus aureus keratitis

Treatment

n

Median (1st quartile – 3rd quartile)

Time after inoculation

5 h

12 h

24 h

36 h

48 h

Vehicle

7

2.50 (2.25–2.75)

13.00 (11.00–15.00)

23.00 (21.25–25.00)

29.00 (25.50–29.75)

25.50 (18.50–25.75)

Azithromycin

0.01%

8

3.50 (2.63–4.00)

12.25 (9.38–13.25)

21.50 (18.75–25.00)

21.00 * (15.75–24.63)

18.25 (15.88–19.88)

 

0.1%

7

3.00 (2.00–3.00)

11.00 (7.50–13.00)

21.50 (8.25–23.25)

21.50 * (13.00–24.50)

22.00 (10.25–22.75)

 

1%

8

2.25 (2.00–3.50)

6.00 * (5.50–6.50)

10.25 * (7.75–12.88)

11.75 * (6.88–16.63)

9.50 * (6.38–12.00)

  1. *p < 0.05 compared with the vehicle (Shirley–Williams test, one-sided)