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Table 4 The incidence rate and incidence rate ratio of cataracts in the systemic lupus erythematosus cohort and comparison cohort (N = 5225)

From: Risks of ophthalmic disorders in patients with systemic lupus erythematosus – a secondary cohort analysis of population-based claims data

Disorder (ICD-9-CM)

 

SLE cohort (n = 468)

comparison cohort (n = 4757)

IRR (95% CI)

Adjusted IRRa (95% CI)

  

No. of patient

Person-years

IR

No. of patient

Person-years

IR

P

P

Cataracts (366)

Overall

62

2844

21.80

274

31,421

8.72

2.50 (1.90–3.29)

< 0.001

3.18 (2.39–4.22)

<  0.001

Sex

 male

9

235

38.30

61

3060

19.93

1.92 (0.96–3.87)

0.067

2.13 (1.03–4.38)

0.041

 female

53

2609

20.31

213

28,361

7.51

2.70 (2.00–3.65)

< 0.001

3.50 (2.56–4.80)

<  0.001

Age group (years)

 20–39

15

 

8.26

 

18,926

0.69

12.03 (5.73–25.28)

< 0.001

13.93 (6.49–29.90)

<  0.001

 40–59

34

1815

36.29

13

10,804

13.24

2.74 (1.89–3.98)

< 0.001

2.78 (1.89–4.09)

<  0.001

  > 60

13

937

141.30

143

1692

69.74

2.02 (1.14–3.59)

0.016

2.03 (1.11–3.71)

0.022

  1. CI Confidence interval, ICD-9-CM International Classification of Diseases, Ninth revision, clinical modification, IR Incidence rate per 1000 person-years, IRR Incidence rate ratio; n.c. Not calculable, SLE Systemic lupus erythematosus
  2. aAdjusted for age, sex, socioeconomic status, and geographic region