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Table 5 The incidence rate and incidence rate ratio of glaucoma in the systemic lupus erythematosus cohort and comparison cohort (N = 5593)

From: Risks of ophthalmic disorders in patients with systemic lupus erythematosus – a secondary cohort analysis of population-based claims data

Disorder (ICD-9-CM)

 

SLE cohort (n = 450)

comparison cohort (n = 4943)

IRR (95% CI)

Adjusted IRRa (95% CI)

  

No. of patient

Person-years

IR

No. of patient

Person-years

IR

P

P

Glaucoma (365)

Overall

18

3116

5.78

96

33,351

2.88

2.01 (1.21–3.32)

0.007

2.23 (1.35–3.70)

0.002

Sex

 male

5

260

19.23

17

3530

4.82

4.00 (1.47–10.83)

0.006

4.25 (1.52–11.88)

0.006

 female

13

2856

4.55

79

29,821

2.65

1.72 (0.96–3.09)

0.071

1.87 (1.03–3.37)

0.038

Age group (years)

 20–39

8

1800

4.44

25

18,875

1.32

3.36 (1.51–7.44) 0.003

3.44 (1.54–7.69) 0.003

 40–59

6

1051

5.71

45

11,183

4.02

1.42 (0.61–3.33)

0.421

1.54 (0.65–3.61)

0.326

  > 60

4

265

15.09

26

3293

7.90

1.91 (0.67–5.48)

0.227

2.14 (0.74–6.20)

0.163

  1. CI Confidence interval, ICD-9-CM International Classification of Diseases, Ninth revision, clinical modification, IR incidence rate per 1000 person-years, IRR Incidence rate ratio, n.c. Not calculable, SLE Systemic lupus erythematosus
  2. aAdjusted for age, sex, socioeconomic status, and geographic region