Risks of ophthalmic disorders in patients with systemic lupus erythematosus – a secondary cohort analysis of population-based claims data

Table 6 The incidence rate and incidence rate ratio of episcleritis and scleritis, retinal vascular occlusion, retinal vasculitis, and neovascular glaucoma in the systemic lupus erythematosus cohort and comparison cohort

Disorder	SLE cohort			comparison cohort			IRR (95% CI)	Adjusted IRR^a (95% CI)
(ICD-9-CM)	No. of patient	Person-years	IR	No. of patient	Person-years	IR	P	P
Episcleritis and scleritis (379.0x) [N = 5715]	8	3186	2.51	13	34,044	0.38	6.57 (2.72–15.86) < 0.001	6.11 (2.39–15.62) < 0.001
Retinal vascular occlusion (362.3x) [N = 5723]	4	3197	1.25	11	34,077	0.32	3.88 (1.23–12.17) 0.020	3.81 (1.21–12.03) 0.023
Retinal vasculitis (362.18) [N = 5731]	1	3215	0.31	1	34,163	0.03	10.63 (0.66–169.89) 0.095	12.00 (0.75–192.41) 0.079
Neovascular glaucoma (365.63) [N = 5730]	1	3218	0.31	0	34,151	n. c.	n. c.	n. c.

CI Confidence interval, ICD-9-CM International Classification of Diseases, Ninth revision, clinical modification, IR Incidence rate per 1000 person-years, IRR Incidence rate ratio, n.c. Not calculable, SLE Systemic lupus erythematosus.
^aAdjusted for age, sex, socioeconomic status, and geographic region

ISSN: 1471-2415