Association of macular thickness with parapapillary atrophy in myopic eyes

Piao, Helong; Guo, Yue; Ha, Jun Young; Sung, Mi Sun; Park, Sang Woo

doi:10.1186/s12886-020-01362-8

BMC Ophthalmology

Table 3 Associations of the thickness of whole macula and each macular layer with microstructure of PPA

From: Association of macular thickness with parapapillary atrophy in myopic eyes

	PPA_+BM				PPA-_BM
	B (95% CI)	P value^a	P value^b	P value^c	B (95% CI)	P value^a	P value^b	P value^c
Central region
OPL	0.004 (−0.003–0.011)	0.210	0.980	0.980	0.010 (− 0.005–0.016)	< 0.001	0.018	0.002
ONL	− 0.005 (− 0.018–0.007)	0.387	0.680	0.803	−0.016 (− 0.026 – − 0.007)	0.001	0.003	0.006
Whole	0.006 (−0.016–0.027)	0.599	0.600	0.831	0.004 (− 0.014–0.021)	0.685	0.266	0.363
Pericentral region
NFL	0.001 (−0.001–0.003)	0.378	0.526	0.789	0.001 (−0.001–0.002)	0.308	0.187	0.306
GCL	−0.002 (− 0.006–0.001)	0.211	0.154	0.468	−0.002 (− 0.005–0.001)	0.161	0.081	0.162
IPL	− 0.002 (− 0.004–0.000)	0.097	0.100	0.468	−0.001 (− 0.002–0.001)	0.269	0.277	0.363
INL	− 0.003 (− 0.006–0.000)	0.094	0.140	0.468	−0.003 (− 0.005–0.000)	0.023	0.040	0.047
OPL	0.000 (− 0.005–0.006)	0.931	0.824	0.927	0.000 (− 0.004–0.004)	0.886	0.303	0.412
ONL	0.001 (− 0.008–0.011)	0.772	0.342	0.559	−0.009 (− 0.016 – − 0.001)	0.025	0.129	0.232
Whole	−0.003 (− 0.018–0.012)	0.673	0.935	0.980	−0.017 (− 0.028 – − 0.005)	0.005	0.011	0.032
Peripheral region
NFL	0.004 (0.001–0.008)	0.056	0.088	0.097	0.000 (−0.003–0.003)	0.846	0.294	0.396
GCL	−0.001 (− 0.004–0.002)	0.421	0.274	0.559	−0.003 (− 0.006 – − 0.001)	0.010	0.931	0.931
IPL	-0.001 (−0.003–0.002)	0.649	0.156	0.468	− 0.002 (− 0.004–0.000)	0.074	0.447	0.502
INL	−0.001 (− 0.003–0.001)	0.407	0.719	0.863	−0.002 (− 0.004–0.000)	0.025	0.519	0.549
OPL	− 0.002 (− 0.004–0.000)	0.100	0.333	0.510	−0.003 (− 0.004 – − 0.002)	< 0.001	0.002	0.005
ONL	0.000 (− 0.006–0.007)	0.890	0.338	0.559	− 0.007 (− 0.011 – − 0.002)	0.008	0.015	0.033
Whole	− 0.001 (− 0.016–0.013)	0.859	0.245	0.364	−0.020 (− 0.031– − 0.009)	< 0.001	0.040	0.047
Subfoveal choroid	− 0.183 (− 0.267 – − 0.098)	< 0.001	0.004	0.007	−0.194 (− 0.257 – − 0.132)	< 0.001	< 0.001	< 0.001

PPA Parapapillary atrophy, PPA_+BM β-parapapillary atrophy with Bruch’s membrane, PPA_-BM β-parapapillary atrophy without Bruch’s membrane, B Unstandardized coefficient, NFL Nerve fiber layer, GCL Ganglion cell layer, IPL Inner plexiform layer, INL Inner nuclear layer, OPL Outer plexiform layer; ONL Outer nuclear layer
^aP value adjusted for age and sex
^bP value adjusted for age, sex, and axial length
^cP value adjusted for age, sex, and axial length. They were adjusted with Benjamini-Hochberg procedure
Values with statistical significance are shown in bold

Back to article page

ISSN: 1471-2415

Contact us

General enquiries: journalsubmissions@springernature.com