Microvascular changes in macula and optic nerve head after femtosecond laser-assisted LASIK: an optical coherence tomography angiography study

Table 2 Vessel density (VD) (Mean ± SD) of macular superficial plexus at baseline and 1 day/1 week/1 month after FS-LASIK

	Baseline (mean ± SD) %	1 day (mean ± SD) %	1 week (mean ± SD) %	1 month (mean ± SD) %
Whole area (6*6mm²)	50.84 ± 0.4	49.98 ± 0.39	50.06 ± 0.49	50.42 ± 0.47
Fovea Region	21.66 ± 1.01	20.03 ± 1.01^*	19.97 ± 0.97^*	20.06 ± 0.94^*
Parafovea Region	53.31 ± 0.54	51.73 ± 0.49	51.89 ± 0.67	52.54 ± 0.6
Perifovea Region	51.56 ± 0.41	50.77 ± 0.43	50.76 ± 0.49	51.09 ± 0.49

VD at baseline was compared with VD at 1 day/1 week/1 month respectively using the repeated-measures analysis. The VD of whole area of SPC had no significantly change after surgery (F(3,132) = 1.41, P = 0.24). The preoperative VD of fovea region was significantly difference from the VD at 1 day/1 week/1 month after surgery (F = (2.71,118.83) = 9.72, P < 0.001). VD at 1 day/1 week/1 month after surgery decreased significantly (P < 0.001). VD of parafovea and perifovea region did not change postoperatively (F(3,132) = 2.27,P = 0.08; F(3,132) = 1.23,P = 0.301, respectively). * represented P < 0.05

ISSN: 1471-2415