Fig. 1
Multimodal imaging of bilateral diffuse uveal melanocytic proliferation secondary to gastric adenocarcinoma. a and b Fundus photography (top left) showed bilateral diffuse oval yellow patches in the posterior pole, corresponding to hypo-fluorescence in autofluorescence (top middle) and hyper-fluorescence in the early and late phases of fundus fluorescein angiography (top right) and indocyanine green angiography (ICGA, bottom middle). Notice the choroidal lesions (white arrows) indicating choroidal melanocytic proliferation in ICGA and spectral domain optical coherence tomography (bottom right). c18F-FDG PET/CT showed an FDG-avid lesion in the gastric antrum (big arrow), and multiple hypermetabolic lymph nodes in perigastric, retroperitoneal, mediastinal and left supraclavicular region (small arrows). d Haematoxylin-eosin staining of the gastric lesion, confirming gastric adenocarcinoma. The neoplastic cells with most deeply-stained nuclei were diffusely distributed (white arrows), mixed with lymphocytes and epithelium