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Table 3 A comparison of baseline characteristics of dry eye and non-dry eye patients based on PD conditions in univariate and multivariate models

From: The association of dry eye syndrome and psychiatric disorders: a nationwide population-based cohort study

Variables

Univariate model

Multivariate modelb

ORa

(95% CI)

p-value

OR

(95% CI)

p-value

Gender

 Women

1.00

(reference)

 

1.00

(reference)

 

 Men

0.52

(0.48–0.56)

< 0.001

0.60

(0.56–0.65)

< 0.001

Age, years

  < 40

1.00

(reference)

 

1.00

(reference)

 

 40–49

1.85

(1.43–2.40)

< 0.001

1.38

(1.06–1.80)

< 0.001

 50–59

3.54

(2.78–4.51)

0.001

2.17

(1.70–2.78)

0.000

 60–69

5.72

(4.52–7.24)

< 0.001

2.97

(2.33–3.79)

0.001

 70–79

11.00

(8.70–13.9)

< 0.001

5.24

(4.10–6.72)

< 0.001

80

11.37

(9.01–14.3)

< 0.001

6.42

(4.98–8.27)

< 0.001

Psychiatric disorder (Yes vs. No)

 Dementia

1.48

(1.35–1.63)

< 0.001

0.73

(0.65–0.82)

< 0.001

 Alcoholic psychoses

0.40

(0.28–0.56)

< 0.001

0.59

(0.42–0.83)

0.003

 Drug psychoses

0.55

(0.40–0.76)

< 0.001

0.85

(0.61–1.18)

0.332

 Schizophrenia

0.69

(0.58–0.81)

< 0.001

1.34

(1.11–1.62)

0.002

 Bipolar disorder

1.83

(1.60–2.08)

< 0.001

1.90

(1.65–2.19)

< 0.001

 Major depression

1.54

(1.43–1.65)

< 0.001

 Paranoid states

0.97

(0.78–1.20)

0.779

1.01

(0.81–1.27)

0.928

 Neurotic disorders

2.68

(2.36–3.05)

< 0.001

1.62

(1.42–1.85)

< 0.001

 Obsessive-compulsive disorders

1.04

(0.86–1.27)

0.682

 Minor depression

1.61

(1.50–1.73)

< 0.001

 Mild mental retardation

0.29

(0.18–0.47)

< 0.001

1.15

(0.69–1.93)

0.597

 Other specified mental retardation

0.08

(0.03–0.22)

< 0.001

0.25

(0.09–0.70)

0.008

 Unspecified mental retardation

0.24

(0.15–0.40

< 0.001

0.84

(0.49–1.43)

0.519

Anti-psychotics

 None

1.00

(reference)

 

1.00

(reference)

 

 First generation

2.06

(1.87–2.27)

< 0.001

1.28

(1.15–1.41)

< 0.001

 Second generation

0.65

(0.44–0.94)

< 0.001

0.64

(0.44–0.95)

0.005

 Both

1.61

(1.42–1.81)

< 0.001

1.07

(0.92–1.23)

0.118

  1. aOR, odds ratio
  2. badjusted for all variables in table