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Table 1 Surgical Management of ARS and Outcomes

From: Surgical outcomes of Glaucoma associated with Axenfeld-Rieger syndrome

Glaucoma Surgery

• Total number of type of glaucoma surgery

• Number of eyes of number of patients

• Average age at time of surgery in years

Previous Glaucoma Surgery (Number of Eyes)

Next Additional Glaucoma Surgery (Number of Eyes)

Years of IOP Control (Range)

Success at Final Follow-up

Goniotomy

• 7 Total Goniotomies

• 6 Eyes of 3 Patients

• 1.7 ± 1.4 years

4 Eyes of 2 Patients

• No Prior Surgeries

3 Eyes of 2 Patients

• Prior Goniotomy (1)

• Prior Trabeculotomy/Trabeculectomy (2)

3 Eyes of 2 Patients

• Trabeculectomy w/anti-fibrotics (3)

4.3 ± 3.9

(2.2-10.1)

• 43% for goniotomy

• 50% for eyes due to multiple goniotomies in 1 eye

Trabeculotomy or Combined Trabeculotomy/ Trabeculectomy

• 6 Total Trabeculotomies ± Trabeculectomies

• 6 Eyes of 4 Patients

• 3.3 ± 7.4 years

6 Eyes of 4 Patients

• No Prior Surgeries

5 Eyes of 3 Patients

• Trabeculectomy w/anti-fibrotics (3)

• Baerveldt© 350 (1)

• Goniotomy (1)

14.8 ± 12.7

(0.4-29.2)

• 17% for trabeculotomy ± trabeculectomy

Trabeculectomy with Anti-Fibrotics

• 18 Total Trabeculectomies with Anti-Fibrotics

• 14 Eyes of 8 Patients

• 16.1 ± 14.8 years

8 Eyes of 5 Patients

• No Prior Surgeries

10 Eyes of 7 Patients

• Prior Trabeculectomy (4)

• Prior Trabeculotomy (2)

• Prior Goniotomy (2)

• Prior Trabeculotomy and Goniotomy (1)

• Prior Ahmed, Baerveldt© 250, Cycloablation (1)

6 Eyes of 5 Patients

• Repeat Trabeculectomy (3)

• Bleb Revision (2)

• Baerveldt© 350 (1)

16.5 ± 13.5

(0.1-39.1)

• 57% for trabeculectomy

• 71% for eyes due to multiple trabeculectomies in 3 eyes

Ahmed© Glaucoma Drainage Device

FP7 (6) and FP8 (3)

• 9 Total Ahmeds©

• 8 Eyes of 5 Patients

• 7.2 ± 7.0 years

8 Eyes of 5 Patients

• No Prior Surgery

1 Eye of 1 Patient

• Prior Ahmed (1)

6 Eyes of 4 Patients

• Cycloablation (1)

• Baerveldt© 250 (3)

• Baerveldt© 350 (1)

• Tube Revision (1)

1.7 ± 1.9

(0.4-6.0)

• 25% for Ahmed© GDDs

Baerveldt© Glaucoma Drainage Device

250 (3)

350 (8)

• 11 Total Baerveldts©

• 9 Eyes of 6 Patients

• 16.8 ± 11.7 years

2 Eyes of 1 Patient

• No Prior Surgery

7 Eyes of 5 Patients

• Prior Trabeculotomy (1)

• Prior Cycloablation (1)

• Prior Ahmed© (4)

• Prior Ahmed©, Cycloablation (1)

• Prior Ahmed©, Baerveldt© 250 (2)a

3 Eyes of 4 Patients

• Endoscopic cycloablation (1)

• Baerveldt© 350 (2)a

1.6 ± 2.1

(0.2-6.7)

• 70% for Baerveldt© GDD

• 88% for eyes due to multiple Baerveldt© GDDs in 2 eyes

Cycloablation

• 6 Total Cycloablations

• 4 Eyes of 3 Patientsb, c

• 16.0 ± 7.8 years

4 Eyes of 3 Patients

• Prior Ahmed© (3)

• Prior Baerveldt© 350 (1)

3 Eyes of 2 Patientsb, c

• Repeat Cycloablation (2)

• Baerveldt© 350 (2)

2.7 ± 3.5

(0.4-9.4)

• 33% for cycloablation

• 50% for eyes due to multiple cycloablations in 2 eyes

  1. a2 eyes with inferonasal Baerveldt© 250 GDDs had subsequent removal of superotemporal Ahmed© FP7 devices and placement of superotemporal Baerveldt© 350 GDDs
  2. b1 eye had endoscopic cycloablation followed by contact transcleral cycloablation
  3. c1 eye had 2 sessions of contact transcleral cycloablation followed by Baerveldt© 350 placement