Comparison of outcomes after topography-modified refraction versus wavefront-optimized versus manifest topography-guided LASIK

Table 2 Change in astigmatism based on the Alpins method of vector analysis

Parameter (mean ± SD)	WFO	Manifest TG	TMR	P-value	Post hoc (P-value)
TIA	0.90 ± 0.50	1.10 ± 0.74	1.17 ± 0.64	.035*	TMR > WFO (.032)
SIA	0.99 ± 0.61	1.13 ± 0.77	1.40 ± 0.75	.002*	TMR > WFO (.002)
DV	0.33 ± 0.31	0.29 ± 0.27	0.47 ± 0.35	.005*	TMR > WFO (.026), Manifest TG (.014)
ME	0.08 ± 0.34	0.03 ± 0.31	0.23 ± 0.39	.007*	TMR > WFO (.041), Manifest TG (.015)
CI	1.10 ± 0.46	1.09 ± 0.47	1.27 ± 0.51	.057
IOS	0.50 ± 0.56	0.43 ± 0.53	0.53 ± 0.51	.607

WFO = wavefront-optimized; TG = topography-guided; TMR = topography-modified refraction; TIA = target-induced astigmatism; SIA = surgically-induced astigmatism; DV = difference vector; ME = magnitude of error; CI = correction index; IOS = index of success. *Statistically significant (P < .05)

ISSN: 1471-2415