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Table 1 Intravitreous Concentrations of LCN2 and VEGF in the PDR and Control Groups

From: Elevated vitreous Lipocalin-2 levels of patients with proliferative diabetic retinopathy

 

PDR Group

Control Group

P

No. of cases

47

20

 

Gender (male: female)

16:31

7:13

0.82

Age (years)

61.32 (7.22)

59.85 (6.90)

0.38

HbAlc (%)

8.16 (2.44)

5.03 (0.51)

< 0.001

VH

32

–

 

TRD

6

–

 

VH + TRD

9

–

 

Idiopathic macular hole

–

20

 

LCN2 (pg/ml)

63,522 (30,009)

1663 (1191)

< 0.001

VEGF (pg/ml)

1038 (1326)

<9a

< 0.001

  1. LCN2 Lipocalin-2, VEGF vascular endothelial growth factor; PDR proliferative diabetic retinopathy, HbAlc glycosylated hemoglobin, VH vitreous hemorrhage, TRD tractional retinal detachment
  2. aVitreous level of VEGF regarded as 9 pg/mL in control participants
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BMC Ophthalmology

ISSN: 1471-2415

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