Fig. 3

Changes in mean visual acuity (logMAR) and CFT in the ischemic and non-ischemic subgroups from baseline to month 12. Mean VA gained from 0.731 ± 0.347 at baseline to 0.385 ± 0.219 at month 12 in the non-ischemic subgroup, and improved from 0.798 ± 0.502 at baseline to 0.507 ± 0.352 at month 12 in the ischemic subgroup (p < 0.001 and P = 0.001, respectively). Similarly, mean CFT reduced from 517.3 μm ± 205.2 μm at baseline to 291.8 μm ± 75.9 μm at month 12 in the non-ischemic subgroup, and 525.1 μm ± 158.5 μm at baseline to 300.1 μm ± 64.7 μm at month 12 in the ischemic subgroup (p < 0.001)