Fig. 2
From: Multimodal imaging features and genetic findings in Bietti crystalline dystrophy
Fundus autofluorescence (AF) images of four BCD patients. a AF image of patient 1 (left eye) showing multiple distinct large patches of hypofluorescence in the macular area, suggesting significant retinal pigment epithelium (RPE) atrophy. The crystals are predominantly present in areas between or around the areas of RPE atrophy. b, c AF images of patient 2 (both eyes) showing small patchy hypofluorescent areas at the posterior pole with partial preservation of the foveal region. d, e AF images of patient 3 (both eyes) showing distinct patchy hypofluorescent areas in the macular area. Similarly, the crystals are present in areas between the areas of RPE atrophy and the healthy retina. f, g AF images of patient 4 showing diffuse hypofluorescence with scattered hyperfluorescence in the posterior pole