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Fig. 1 | BMC Ophthalmology

Fig. 1

From: MiR-221/SIRT1/Nrf2 signal axis regulates high glucose induced apoptosis in human retinal microvascular endothelial cells

Fig. 1

Expression of miR-221 in hRMEC was high while that of SIRT1 was low in high glucose condition. a: Detection of the expression of miR-221 in hRMEC under NG and HG conditions by qRT-PCR. (** indicates P < 0.01). b: Detection of SIRT1 mRNA expression in hRMEC under NG and HG conditions by RT-PCR. (* indicates P < 0.05). c: Detection of SIRT1 protein expression in hRMEC under NG and HG conditions by WB assay. Full-length blots are presented in Supplementary Figure 1C. Statistical analysis of relative SIRT1 expression level was conveyed and displayed in columns (* indicates P < 0.05). GAPDH served as loading control

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BMC Ophthalmology

ISSN: 1471-2415

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