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Table 2 Comparison of change in various ocular properties between medical treatment group and no treatment control for myopic regression in post-LASIK eyes

From: Reduction of corneal epithelial thickness during medical treatment for myopic regression following FS-LASIK

 

Medical treatment group (n = 84)

No treatment control (n = 33)

P*

Initial

End

P

Initial

End

P

Sphere

−1.04 ± 0.40

−0.88 ± 0.51

0.001

− 0.20 ± 0.40

−0.34 ± 0.46

0.012

< 0.001

(D)

(−2.0, − 0.50)

(− 2.3, 0.50)

 

(− 1.0, 0)

(−1.25, 0)

  

Cylinder

−0.46 ± 0.30

−0.49 ± 0.25

0.251

−0.44 ± 0.23

−0.48 ± 0.28

0.226

0.840

(D)

(−1.5, 0)

(−1.25, 0)

 

(−1.0, 0)

(− 1.5, 0)

  

SE (D)

−1.26 ± 0.41

−1.13 ± 0.51

0.010

−0.42 ± 0.39

−0.58 ± 0.45

0.004

< 0.001

 

(− 2.25, − 0.63)

(− 2.63, 0.38)

 

(−1.13, − 0.5)

(− 1.5, − 0.38)

  

UDVA

0.25 ± 0.12

0.17 ± 0.15

< 0.001

− 0.07 ± 0.05

− 0.07 ± 0.05

0.801

< 0.001

(logMAR)

(0.05, 0.5)

(−0.1, 0.5)

 

(−0.1, 0.1)

(− 0.1, 0.1)

  

IOP

11.3 ± 1.4

10.4 ± 1.8

< 0.001

11.2 ± 1.9

10.8 ± 1.5

0.062

0.084

(mmHg)

(9, 16)

(7, 15)

 

(8, 17)

(8, 15)

  

CET (μm)

60.2 ± 4.8

54.2 ± 2.7

< 0.001

56.1 ± 3.5

55.5 ± 4.31

0.173

< 0.001

 

(53, 75)

(49, 65)

 

(48, 63)

(47, 68)

  

mET (μm)

60.0 ± 3.8

55.2 ± 3.1

< 0.001

58.6 ± 3.8

58.0 ± 4.0

0.218

< 0.001

 

(53.9, 71.6)

(49.1, 65.6)

 

(50.1, 64.9)

(49., 69)

  

pET (μm)

57.0 ± 3.0

53.7 ± 3.0

< 0.001

56.7 ± 3.1

56.7 ± 3.2

0.662

< 0.001

 

(51.1, 64.3)

(47.4, 62.9)

 

(50.1. 63.3)

(49.1, 65)

  

ST (μm)

412.9 ± 28.1

413.8 ± 27.8

0.06

411.0 ± 25.3

412.7 ± 26.9

0.102

0.620

 

(352, 477)

(358, 477)

 

(350, 471)

(350, 474)

  

K (D)

38.9 ± 1.8

38.5 ± 1.9

< 0.001

38.7 ± 1.5

38.6 ± 1.6

0.134

0.004

 

(35.0, 41.8)

(34.5, 42.0)

 

(36.0, 41.5)

(35.8, 42)

  

PC (mm)

6.34 ± 0.25

6.31 ± 0.25

< 0.001

6.34 ± 0.23

6.31 ± 0.22

0.006

0.954

 

(5.93, 7.06)

(5.78, 6.97)

 

(5.81, 6.74)

(5.84, 6.74)

  
  1. Mean ± SD (min, max) values were presented; SE spherical equivalent, UDVA uncorrected distant visual acuity, logMAR logarithm of the minimum angle of resolution, IOP intraocular pressure, CET central corneal epithelial thickness, mET paracentral epithelial thickness, pET pericentral epithelial thickness, ST stromal thickness at center, K Corneal power measured using ARK, D diopters, PC posterior corneal radius of curvature measured using Pentacam. P: comparison between initial measurement and end measurement using paired t-test. P*: comparison of differences between treatment group and no treatment using independent t-test
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BMC Ophthalmology

ISSN: 1471-2415

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