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Table 3 Comparison of characteristics between subgroups formed based on corneal epithelial thickness at the initiation of medical treatment for myopic regression after LASIK

From: Reduction of corneal epithelial thickness during medical treatment for myopic regression following FS-LASIK

 

Group 1

CET ≤ 57

(n = 26)

Group 2

58 ≤ CET ≤ 61

(n = 32)

Group 3

CET ≥ 62

(n = 26)

P

Preop SE (D)

−4.4 ± 2.0

−4.9 ± 1.8

−6.5 ± 2.0

0.001

Age at operation

23.8 ± 5.3

24.3 ± 4.6

26.5 ± 4.4

0.070

CCTini (μm)

477.0 ± 26.6

474.2 ± 24.8

469.4 ± 27.3

0.546

CETini (μm)

55.6 ± 1.3

59.2 ± 1.1

65.9 ± 4.0

< 0.001

Good response (%)

1 (3.8)

6 (18.8)

20 (76.9)

< 0.001

No response (%)

15 (57.7)

13 (40.6)

1 (3.8)

< 0.001

SEini (D)

−1.18 ± 0.38

− 1.22 ± 0.39

−1.40 ± 0.45

0.126

dCET (μm)

−3.1 ± 2.0

−5.4 ± 2.6

−9.4 ± 3.3

< 0.001

 

(−6, 1)

(− 11, 1)

(− 17, − 5)

 

dSE (D)

−0.08 ± 0.35

0.04 ± 0.34

0.48 ± 0.55

< 0.001

 

(− 1.25, 0.50)

(− 0.75, 0.75)

(− 0.50, 1.88)

 

dUDVA

− 0.00 ± 0.11

− 0.04 ± 0.09

− 0.18 ± 0.11

0.001

 

(−0.25, 0.35)

(−0.25, 0.1)

(− 0.4, − 0.05)

 

dK

−0.09 ± 0.25

−0.16 ± 0.26

−0.57 ± 0.37

0.001

 

(−0.75, 0.5)

(− 0.5, 0.25)

(− 1.25, 0.25)

 
  1. Mean ± SD (min, max) values were presented; CET central corneal epithelial thickness, SE spherical equivalent, ini initial, before treatment, d delta (measurement at the end – initial measurement, UCVA uncorrected visual acuity, K Corneal power measured using ARK, D diopters. P: comparison using one-way ANOVA