Assessment of tear film lipid layer thickness in patients with Meibomian gland dysfunction at different ages

BMC Ophthalmology

Table 3 Correlations between average LLT and clinical parameters

Variables	All group (n = 209)		Young group (n = 77)		Middle-aged group (n = 52)		Older group (n = 80)
Variables	r	P	r	P	r	P	r	P
OSDI score	−0.035	0.614	−0.020	0.866	−0.015	0.917	0.026	0.820
Lid margin abnormality	0.018	0.792	0.076	0.513	−0.189	0.181	−0.014	0.901
MGE score	0.202	0.003	0.007	0.949	0.280	0.044	0.452	< 0.001
Schirmer’s I test (mm)	−0.067	0.338	0.026	0.824	0.186	0.187	−0.134	0.235
ITBUT (sec)	−0.007	0.919	− 0.097	0.403	−0.058	0.682	0.148	0.189
CFS score	−0.135	0.052	−0.064	0.581	−0.156	0.269	−0.200	0.075
NITBUT (sec)	0.020	0.778	−0.040	0.732	0.115	0.418	0.026	0.816
Central TMH (mm)	−0.067	0.336	−0.066	0.571	−0.018	0.898	−0.007	0.498
MG dropout (%)	−0.527	< 0.001	−0.536	< 0.001	− 0.576	< 0.001	−0.501	< 0.001

OSDI Ocular surface disease index; LLT Lipid layer thickness; MGE Meibomian gland evaluator, ITBUT Invasive tear break-up time; CFS Corneal fluorescein staining; NITBUT Non-invasive tear break-up time; TMH tear meniscus height
Significant data are in bold face

ISSN: 1471-2415