Fig. 2

Mean change from baseline in BCVA and CRT at Months 3 and 12 by loading and non-loading dose subgroups. *P < 0.0001 (95% CI 2.8–6.7); **P = 0.0266; ***P < 0.001. ∆ represents mean gain in BCVA or mean reduction in CRT. indicates mean number of injections. BCVA: baseline, loading n = 117, non-loading n = 34; Month 3, loading n = 106, non-loading n = 29; Month 12, loading n = 76, non-loading n = 17. CRT: baseline, loading n = 117, non-loading n = 34; Month 3, loading n = 100, non-loading n = 30; Month 12, loading n = 65, non-loading n = 20. BCVA, best-corrected visual acuity; CRT, central retinal thickness; ETDRS, Early Treatment for Diabetic Retinopathy Study; n, number of patients