Table 2 The adverse effects on the different dose of atropine studies

Chua et al.,2005 [10]

1

No serious adverse events. Reasons for withdrawal: allergic or hypersensitivity reactions or discomfort (4.5%), glare (1.5%), blurred near vision (1%), logistical difficulties (3.5%), and others (0.5%).

Polling et al., 2016 [13]

0.5

Photophobia (72.4%); reading problems (37.7%); headaches(22.4%); systemic flushes (only in a minority); pain in the eye, irritated eyes, overflow of tears, trouble with depth perception, cosmetically disfiguring pupils, and an unpleasant taste in mouth (all reported only in one patient).

Yam et al.,2018 [17]

0.05

Gastroenteritis, influenza, or asthmatic attack(1 case)

YEN et al., 1989 [18]

1

Photophobia (100%), No systemic or ocular complications

Yi et et al., 2015 [19]

1

No complain