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Table 4 Mean Change in Avascular Zone by Fluorescein Angiography During the Study

From: Sub-optimal gain in vision in retinal vein occlusion due to under-treatment in the real world: results from an open-label prospective study of Intravitreal Ranibizumab

 

Mean (SD) of FAZ Diameter (mm)

Mean (SD) of FAZ Area (mm2)

 

Baseline n = 46

Week 12 n = 24

Week 24

n = 14

Week 48

n = 16

Baseline

n = 46

Week 12

n = 24

Week 24

n = 14

Week 48

n = 17

Mean (SD)

0.81 (0.396)

0.71 (0.363)

0.83 (0.519)

0.70 (0.389)

0.46 (0.322)

0.33 (0.246)

0.40 (0.408)

0.33 (0.212)

Change from Baseline

−0.01 (0.361)

0.20 (0.343)

0.10 (0.440)

−0.04 (0.214)

0.07 (0.297)

−0.00 (0.203)

95% Confidence Interval

−0.16, 0.14

0.00, 0.40

−0.14, 0.33

−0.13, 0.05

− 0.10, 0.25

−0.11, 0.10

p-value*

0.8964

0.0477

0.3835

0.3713

0.3665

0.9370

  1. *p-value calculated using unpaired t-test
  2. FAZ Foveal Avascular Zone -Diameter (in millimeters); FAZ Foveal Avascular Zone-Area (in squared millimeters)