Fig. 1

Patient example of primary geographic atrophy (GA) due to age-related macular degeneration complicated by the development of a choroidal neovascularization (CNV). Fourteen months after the baseline exam (a), a type 2 choroidal neovascularization (white *) was diagnosed on the lower border of the GA (b) and successfully treated with three monthly anti-VEGF injections. Due to reactivation, two further anti-VEGF injections were given, resulting in a morphologically partially fibrotic PED. On OCT, the areas of hypertransmission increased during follow-up. At the end of follow-up 21 months after the last anti-VEGF injection (c), the GA had considerably enlarged more in the three directions (nasally, temporally, superiorly) not affected by the CNV (lower aspect of GA)