Fig. 4
a Change in GA enlargement rate correlated with the total amount of anti-VEGF injections given. Change in enlargement speed was defined as the ratio of growth rate after CNV diagnosis until end of follow-up, divided by the growth rate prior to CNV diagnosis. Pearson correlation revealed no connection between changes in growth rate and the total or yearly amount of anti-VEGF injections given (total: r = 0.58; p = 0.23; yearly: r = 0.52; p = 0.30). Besides, no other investigated factor was found to be relevant (baseline GA size: r = − 0.06, p = 0.91; number of baseline GA lesions: r = 0.45, p = 0.38; subfoveal choroidal thickness: r = − 0.26, p = 0.62; age: r = − 0.04, p = 0.94; number of visits with IRF presence: r = − 0.44, p = 0.38). b Individual study eye growth rates pre- and post-CNV in mm2/year (x-axis and right y-axis) stratified by anti-VEGF injection number on the left y-axis. Higher cumulative anti-VEGF injection count did not correlate with growth rate acceleration