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Table 3 Factors affecting repetitive measurements of BCVAa for 1 year

From: Title: efficacy of intravitreal dexamethasone implant on hard exudate in diabetic macular edema

Variable

Beta

P value

 
  

Univariableb

Multivariableb

Male

4.824

0.47

 

Presence of SRF

-8.378

0.174

 

Diffuse type DME

-2.128

0.729

 

Age

-0.594

0.038*

0.011*

HbA1c

-3.842

0.035*

0.164

BUN

-0.583

0.445

 

Cr

4.354

0.142

 

TG

-0.011

0.75

 

Total cholesterol

0.01

0.866

 

HDL

0.055

0.768

 

LDL

0.061

0.502

 

Microaneurysm count

-0.382

0.014*

0.201

IOP increase (> 25 mmHg)

0.212

0.758

 

Cataract progression

-0.321

0.132

 

HE areaa

-0.807

0.383

 

HE1500 areaa

-4.457

< 0.001*

0.004*

CMTa

-0.042

0.001*

< 0.001*

  1. BCVA best corrected visual acuity, Presence of SRF presence of macular subretinal fluid, DME diabetic macular edema, BUN blood urea nitrogen, Cr creatinine, TG triglyceride, HDL high density lipoprotein, LDL low density lipoprotein, IOP intraocular pressure, HE hard exudate, HE1500 HE within 1500 µm from the fovea, CMT central macular thickness
  2. *P value less than 0.05
  3. aBCVA, HE area and HE1500 area indicates the values observed in every visit of all the study participants. Because they were clustered data of the same person, generalized estimating equation (GEE) was used as statistical analysis
  4. bThe outcome variable was BCVA. The within-subject variable was the visit month. An autoregressive correlation was used as a working correlation