Fig. 9

Selection of candidate genes based on their expression profile. Genes were first filtered with the bioinformatics formula DE vs NE + DE ≠ NR. Two profiles of expression were then selected, for which the risk of contamination by photoreceptor genes is minimal. a. The first profile corresponds to genes expressed only in DE (DE+, e.g. Lrg1). b The second profile corresponds to genes expressed in DE and in DR (DE+/DR+, e.g. Lcn2). c The third profile corresponds to genes whose expression is down-regulated in DE versus NE (DE-, e.g. Lamc3)