Table 3 Identification of functions enriched in endothelial cells during EAU
Function | Fold enrichment (DE/NE) | P-value |
|---|---|---|
Inflammatory response | 6,2 | 8,0 × 10− 4 |
Innate immunity | 6,0 | 2,8 × 10− 2 |
Cytokine activity | 5,5 | 3,4 × 10− 2 |
Selectin superfamily | 228,8 | 8,6 × 10− 3 |
Cell adhesion | 3,8 | 1,9 × 10− 2 |
Leukocyte tethering or rolling | 40,9 | 4,7 × 10− 2 |
Complement activation | 40,9 | 4,7 × 10− 2 |
Extracellular matrix | 4,5 | 5,8 × 10− 2 |
Positive regulation of angiogenesis | 10,1 | 6,9 × 10− 3 |