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Table 2 Adherence to fixed- and unfixed-combination therapies during the 12-month post-index period

From: Comparison of adherence between fixed and unfixed topical combination glaucoma therapies using Japanese healthcare/pharmacy claims database: a retrospective non-interventional cohort study

 

All patients

N = 638

Fixed combination

N = 309

Unfixed combination

N = 329

 

PDC, mean ± SD (%)

70.4 ± 362

79.1 ± 32.1

62.2 ± 38.0

P < 0.0001a

 

n (%)

n (%)

n (%)

 

80 + % PDC

375 (58.8)

215 (69.6)

160 (48.6)

P < 0.0001b

< 80% PDC

263 (41.2)

94 (30.4)

169 (51.4)

 

60–79% PDC

46 (7.2)

16 (5.2)

30 (9.1)

 

40–59% PDC

43 (6.7)

24 (7.8)

19 (5.8)

 

20–39% PDC

54 (8.5)

19 (6.1)

35 (10.6)

 

< 20% PDC

120 (18.8)

35 (11.3)

85 (25.8)

 
  1. PDC proportion of days covered
  2. a, t-test (fixed vs. unfixed); b, χ2 test (fixed vs. unfixed). Note: a p-value < 0.05 / 9 (= 0.00556) was considered statistically significant (by Bonferroni correction)
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BMC Ophthalmology

ISSN: 1471-2415

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