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Table 2 Adherence to fixed- and unfixed-combination therapies during the 12-month post-index period

From: Comparison of adherence between fixed and unfixed topical combination glaucoma therapies using Japanese healthcare/pharmacy claims database: a retrospective non-interventional cohort study

  All patients
N = 638
Fixed combination
N = 309
Unfixed combination
N = 329
 
PDC, mean ± SD (%) 70.4 ± 362 79.1 ± 32.1 62.2 ± 38.0 P < 0.0001a
  n (%) n (%) n (%)  
80 + % PDC 375 (58.8) 215 (69.6) 160 (48.6) P < 0.0001b
< 80% PDC 263 (41.2) 94 (30.4) 169 (51.4)  
60–79% PDC 46 (7.2) 16 (5.2) 30 (9.1)  
40–59% PDC 43 (6.7) 24 (7.8) 19 (5.8)  
20–39% PDC 54 (8.5) 19 (6.1) 35 (10.6)  
< 20% PDC 120 (18.8) 35 (11.3) 85 (25.8)  
  1. PDC proportion of days covered
  2. a, t-test (fixed vs. unfixed); b, χ2 test (fixed vs. unfixed). Note: a p-value < 0.05 / 9 (= 0.00556) was considered statistically significant (by Bonferroni correction)
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