Skip to main content

Table 2 Extracted genotype data from the included studies

From: Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis

Variant Controls (n) Cases (n) Study Cases Controls PHWE MAF
UCP1 rs1800592     GG GA AA G A GG GA AA G A   
DWR (2260) DR (1386) Jin 2017 140 251 139 531 529 338 669 338 1345 1345 0.85 50%
   Rudofsky 2007 5 63 60 73 183 18 173 198 209 569 0.01 27%
   Zhang 2014 122 217 105 461 427 79 161 94 319 349 0.53 50%
   Zietz 2006 8 72 114 88 300 15 117 183 147 483 0.50 23%
DWR (649) NPDR (366) Zhang 2014 57 110 60 224 230 79 161 94 319 349 0.53 48%
   Zietz 2006 6 49 84 61 217 15 117 183 147 483 0.50 23%
DWR (649) PDR (272) Zhang 2014 65 107 45 237 197 79 161 94 319 349 0.53 50%
   Zietz 2006 2 23 30 27 83 15 117 183 147 483 0.50 24%
UCP2 rs659366     AA AG GG A G AA AG GG A G   
DWR (2244) DR (1236) Jin 2017 68 261 201 397 663 177 654 513 1008 1680 0.16 37%
   Rudofsky 2007 17 62 49 96 160 49 186 154 284 494 0.54 37%
   Shen 2014 59 144 102 262 348 38 73 38 149 149 0.81 45%
   Zhou 2018 57 122 30 236 182 33 110 56 176 222 0.09 50%
DWR (348) NPDR (194) Shen 2014 23 54 25 100 104 38 73 38 149 149 0.81 50%
   Zhou 2018 25 61 6 111 73 33 110 56 176 222 0.09 49%
DWR (606) PDR (560) Crispim 2010 45 131 64 221 259 30 116 112 176 340 1.00 40%
   Shen 2014 36 90 77 162 244 38 73 38 149 149 0.81 44%
   Zhou 2018 32 61 24 125 109 33 110 56 176 222 0.09 48%
  1. DWR diabetes without retinopathy, DR diabetic retinopathy, PDR proliferative diabetic retinopathy, NPDR non-proliferative diabetic retinopathy, HWE Hardy-Weinberg equilibrium, MAF minor allele frequency, n: number
\