Table 4 Subgroup analysis on subtype of DR and ethnicity
Variant | Cases vs Controls | Ethnicity | Allelic | Homozygous | Heterozygous | Dominant | Recessive |
|---|---|---|---|---|---|---|---|
OR (95% C.I.) | OR (95% C.I.) | OR (95% C.I.) | OR (95% C.I.) | OR (95% C.I.) | |||
UCP1 rs1800592 |  |  | G vs A | GG vs AA | AG vs AA | GG + AG vs AA | GG vs AG + AA |
NPDR vs DWR | Â | 1.02 (0.84,1.23) | 1.08 (0.71,1.64) | 0.99 (0.74,1.33) | 1.00 (0.76,1.32) | 1.05 (0.73,1.52) | |
PDR vs DWR | Â | 1.26 (1.02,1.56)* | 1.60 (1.01,2.52)* | 1.32 (0.93, 1.87) | 1.38 (0.99,1.92) | 1.32 (0.91,1.92) | |
UCP2 rs659366 |  |  | A vs G | AA vs GG | GA vs GG | AA+GA vs GG | AA vs GA + GG |
NPDR vs DWR | Â | 1.36 (0.69,2.67) | 2.48 (0.33, 18.37) | 2.33 (0.51,10.57) | 2.35 (0.45, 12.43) | 1.26 (0.58,2.75) | |
PDR vs DWR | Â | 1.17 (0.67,2.05) | 1.40 (0.46,4.24) | 1.17 (0.57,2.40) | 1.22 (0.54,2.77) | 1.28 (0.63,2.56) | |
UCP1 rs1800592 |  |  | G vs A | GG vs AA | AG vs AA | GG + AG vs AA | GG vs AG + AA |
DR vs DWR | Chinese | 1.05 (0.94, 1.16) | 1.12 (0.89,1.40) | 1.00 (0.82,1.22) | 1.04 (0.86,1.26) | 1.12 (0.93,1.35) | |
| Â | Total | 1.03 (0.93, 1.13) | 1.10 (0.88,1.37) | 1.00 (0.84,1.19) | 1.03 (0.87,1.21) | 1.11 (0.92, 1.33) | |
UCP2 rs659366 |  |  | A vs G | AA vs GG | GA vs GG | AA+GA vs GG | AA vs GA + GG |
DR vs DWR | Chinese | 0.99 (0.74, 1.34) | 1.20 (0.52,2.76) | 1.13 (0.70,1.83) | 1.15 (0.65,2.03) | 1.08 (0.65,1.77) | |
| Â | Total | 1.00 (0.79,1.27) | 1.17 (0.63,2.17) | 1.10 (0.79,1.55) | 1.12 (0.75,1.67) | 1.07 (0.73,1.57) |