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Table 1 Clinical characteristics of the study cohort

From: Validation of the DIGIROP-birth model in a Chinese cohort

Variables

No TR-ROP (n = 349)

TR-ROP (n = 93)

P

 

Mean (SD)

Mean (SD)

 

Maternal factors

 Maternal age, years

  

0.451

  25–30

125 (36.9)

30 (33.0)

 

  < 25

60 (17.7)

16 (17.6)

 

  30–35

101 (29.8)

29 (31.9)

 

  > 35

53 (15.6)

16 (17.6)

 

 Caesarean delivery

135 (38.7)

29 (31.2)

0.183

 Multiple gestations

81 (23.2)

15 (16.1)

0.141

 In vitro fertilization

43 (12.3)

10 (10.8)

0.679

 Gestational hypertension

23 (6.7)

10 (10.8)

0.175

 Gestational diabetes

54 (15.5)

15 (16.1)

0.877

 Reproductive tract infections during pregnancy

31 (8.9)

5 (5.4)

0.272

 Antenatal steroids use

82 (23.5)

14 (15.1)

0.079

Neonatal factors

 Gestational age, weeks

29.0 ± 1.2

28.2 ± 1.5

< 0.001

 Birth weight, g

1267.8 ± 230.5

1121.5 ± 226.3

< 0.001

 Male

234 (67.0)

52 (55.9)

0.046

 Apnea

97 (27.8)

36 (38.7)

0.041

 Respiratory distress syndrome

263 (75.4)

75 (80.6)

0.285

 Bronchopulmonary dysplasia

197 (56.4)

62 (66.7)

0.075

 Sepsis

105 (30.1)

27 (29.0)

0.891

 Necrotizing enterocolitis

36 (10.3)

14 (15.1)

0.2

 Intraventricular hemorrhage

130 (37.2)

46 (49.5)

0.034

 Patent ductus arteriosus

130 (37.2)

36 (38.7)

0.796

 Anaemia

178 (51.0)

49 (52.7)

0.804

 Hyperbilirubinemia

215 (61.6)

53 (57.0)

0.418

Neonatal interventions

 Invasive mechanical ventilation

325 (93.1)

87 (93.5)

0.885

 Blood transfusions

305 (87.4)

88 (94.6)

0.074

  1. SD Standard deviation, TR-ROP Treatment-requiring retinopathy of prematurity