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Table 1 Demographic information and study parameters in moderate (n = 372 eyes) and high (n = 171 eyes) myopic patients treated with SMILE, femto-LASIK, and PRK in this study

From: Matched comparison of corneal higher order aberrations induced by SMILE to femtosecond assisted LASIK and to PRK in correcting moderate and high myopia: 3.00mm vs. 6.00mm

  Moderate myopia High myopia
SMILE femto-LASIK PRK SMILE femto-LASIK PRK
Number of eyes 124 124 124 57 57 57
Age (years) 28.02 ± 5.22 28.21 ± 4.71 28.31 ± 6.32 27.76 ± 6.39 30.29 ± 7.63 28.79 ± 7.00
Sex (F) 66.1 % 62.9 % 64.5 % 61.8 % 58.8 % 63.6 %
ACT (µm) 561.08 ± 25.88 561.03 ± 25.88 560.73 ± 25.87 544.56 ± 17.26 551.00 ± 16.50 543.62 ± 18.66
Removal tissue thickness (µm) 106.63 ± 13.51 76.43 ± 13.79 73.41 ± 13.61 143.53 ± 16.28 112.33 ± 11.63 112.56 ± 12.38
MRSE (D) Pre-op -4.66 ± 0.85 -4.47 ± 0.82 -4.36 ± 0.72 -7.54 ± 0.92 -7.19 ± 0.61 -7.79 ± 1.37
After 12 M 0.15 ± 0.34 -0.00 ± 0.33 0.10 ± 0.35 -0.05 ± 0.47 -0.31 ± 0.28 -0.27 ± 0.58
Astigmatism (D) Pre-op -1.00 ± 0.80 -0.80 ± 0.58 -0.93 ± 0.71 -1.64 ± 1.15 -1.56 ± 1.41 -1.51 ± 0.91
After 12 M -0.40 ± 0.40 -0.39 ± 0.29 -0.45 ± 0.29 -0.57 ± 0.53 -0.50 ± 0.05 -0.37 ± 0.20
UDVA (logMAR) Pre-op 1.40 ± 0.26 1.37 ± 0.28 1.40 ± 0.14 1.75 ± 0.15 1.62 ± 0.33 1.73 ± 0.21
After 12 M 0.01 ± 0.03 0.00 ± 0.00 0.00 ± 0.02 0.01 ± 0.03 0.02 ± 0.06 0.05 ± 0.13
CDVA (logMAR) Pre-op 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.01 ± 0.03 0.00 ± 0.00 0.02 ± 0.04
After 12 M 0.00 ± 0.01 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00 0.01 ± 0.02 0.01 ± 0.02
Safety index 0.99 ± 0.03 1.00 ± 0.00 1.00 ± 0.00 1.04 ± 0.07 0.98 ± 0.04 1.04 ± 0.07
Efficacy index 0.99 ± 0.02 1.00 ± 0.00 1.00 ± 0.00 1.04 ± 0.07 0.98 ± 0.04 1.04 ± 0.07
  1. SMILE small incision lenticule extraction, femto-LASIK femtosecond-assisted laser in-situ keratomileusis, PRK photorefractive keratectomy with mitomycin-C, ACT apical corneal thickness, MRSE manifest refraction spherical equivalent, UDVA uncorrected distance visual acuity, CDVA corrected distance visual acuity
  2. Removal tissue thickness: maximum lenticule thickness in SMILE and ablation depth in femto-LASIK and PRK