Potential effects of angiogenesis-related factors on the severity of APAC and surgical outcomes of trabeculectomy

BMC Ophthalmology

Table 5 Aqueous humor analysis of EPO and PDGF family members concentration in success and failure groups

Analyte	Success	Failure	Median difference (95% CI)	P
EPO, Medium (IQR), pg/ml	28.44 (10.50)	48.60 (40.68)	-16.74 (-37.22~-6.24)	0.008*
PDGF-AA, Medium (IQR), pg/ml	1.62 (0.71)	2.14 (1.18)	-0.50 (-1.06~0.04)	0.074
PDGF-BB, Medium (IQR), pg/ml	0.16 (0.04)	0.18 (0.12)	-0.02 (-0.06~0.00)	0.164
PDGF-CC, Medium (IQR), pg/ml	1.70 (0.42)	2.46 (7.14)	-0.72 (-2.32~-0.30)	0.003*
PDGF-DD, Medium (IQR), pg/ml	0.08 (0.12)	0.18 (0.28)	-0.060 (-0.20~0.00)	0.045*

Note: Mann-Whitney U test was used to investigate the difference of EPO, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD between success and failure patients’ aqueous humor. *P<0.05
APAC acute primary angle closure, IQR interquartile-range

ISSN: 1471-2415