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Fig. 3 | BMC Ophthalmology

Fig. 3

From: Safety evaluation of the atmospheric low-temperature plasma (ALTP) on the conjunctiva: an animal study and histopathological findings; 6-month follow-up

Fig. 3

H&E-stained histological section of conjunctiva shows a slightly decreased vascularity, a diffused stromal swelling with extensive separation of collagen fibers, and a superficial epithelium loss following one week of the plasma exposure (a) [original magnification × 100 (H&E)]. The progression of re-epithelialization with subsidence of edema was noticed in one-month post-exposure (b) [original magnification × 100 (H&E)]. Histological sections after three months (c) [original magnification × 400 (H&E)] and six months (d) [original magnification × 400 (H&E)] post-exposure show that re-epithelialization is completed, stromal edema is resolved, and the conjunctival vascularization is restored. Of note, conjunctiva has returned to its normal histological order with no signs of chronic inflammation, hemorrhage, scar tissue, atypia, and dysplasia in the plasma exposed section. *Two blue lines show the plasma exposed areas of the conjunctiva

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