Relationship between structural and functional changes in glaucomatous eyes: a multifocal electroretinogram study

BMC Ophthalmology

Table 4 Correlations between the mfPhNR/B of mfERG in each sector and the average thickness of the GCIPL, mRNFL, and GCC of OCT in glaucoma patients

Sectors	IQR	Coefficient	95% LCL	95% UCL	P-value
mfPhNR/B	vs GCIPL average
Center	0.259–0.385	0.839	−1.456	3.133	0.739
Superotemporal	0.151–0.261	−0.025	−3.793	3.743	0.033
Superonasal	0.160–0.240	1.013	−1.956	3.982	0.649
Inferonasal	0.192–0.306	1.096	−1.831	4.024	0.726
Inferotemporal	0.194–0.304	2.459	−0.791	5.71	0.042
	vs mRNFL average
Center	0.259–0.385	0.863	−0.720	2.446	0.551
Superotemporal	0.151–0.261	1.04	−1.443	3.523	0.228
Superonasal	0.160–0.240	1.283	−0.919	3.485	0.483
Inferonasal	0.192–0.306	1.492	−0.414	3.399	0.301
Inferotemporal	0.194–0.304	2.363	0.416	4.31	0.003
	vs GCC average
Center	0.259–0.385	1.701	−2.049	5.451	0.650
Superotemporal	0.151–0.261	1.015	−5.103	7.134	0.061
Superonasal	0.160–0.240	2.296	−2.778	7.370	0.642
Inferonasal	0.192–0.306	2.588	−2.076	7.253	0.540
Inferotemporal	0.194–0..304	4.823	−0.234	9.88	0.012

Coefficient represents the increase in the value of mfPhNR/B in each sector when GCIPL average, mRNFL average or GCC average changes by 75th percentile from 25th percentile. All multivariable regression models were adjusted for age and spherical equivalent
mfPhNR/B multifocal photopic negative response to multifocal B-wave ratio, mfERG multifocal electroretinogram, GCIPL Ganglion cell-inner plexiform layer, mRNFL Macular retinal nerve fiber layer, GCC Ganglion cell complex, OCT Optical coherence tomopraphy, IQR interquartile range (25th percentile – 75th percentile), LCL lower confidence limit, UCL upper confidence limit

ISSN: 1471-2415