Variants identified by next-generation sequencing cause endoplasmic reticulum stress in Rhodopsin-associated retinitis pigmentosa

Table 1 Clinical features for affected members of two adRP families

Family ID	Patient number	Age(year)^a/Sex	Onset age (year)^b	VA		Cataract	Visual field	Glaucoma
Family ID	Patient number	Age(year)^a/Sex	Onset age (year)^b	O.D	O.S	Cataract	Visual field	Glaucoma
Family JH	III-2	67/F	10	FC	FC	YES	Unable to cooperate	YES
	III-8	58/M	15	0.2	0.2	YES	Constriction	YES
	III-4	65/F	12	0.12	0.1	YES	Constriction	NO
	IV-6	45/M	10	0.4	0.4	NO	Constriction	NO
	V-1	22/F	12	0.6	0.6	NO	N/A	NO
Family HD09	III-2	58/F	3	0.1	0.1	YES	N/A	YES
	III-3	56/M	3	FC	0.1	YES	N/A	YES
	III-5	51/M	4	NLP	NLP	YES	N/A	YES
	IV-4	35/F	5	0.4	0.4	NO	Constriction	NO
	IV-5	33/M	4	0.2	0.1	NO	N/A	NO
	IV-10	34/F	3	0.25	0.2	NO	N/A	NO
	IV-12	29/M	4	0.25	0.5	NO	N/A	NO
	IV-14	28/F	5	0.4	0.5	NO	N/A	NO
	V-3	7/F	3	0.6	0.6	NO	N/A	NO

^aAge of recruitment and examination; ^bOnset age of night blindness; Abbreviations: VA visual acuity, O.D. right eye, O.S. left eye, FC finger count, NLP no light perception, N/A not available

ISSN: 1471-2415