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Table 2 Analysis of 4 SNPs in NDR and PDR groups

From: Association of four gene polymorphisms in Chinese Guangxi population with diabetic retinopathy in type 2 diabetic patients

Gene SNP Allele NDR [%] PDR [%] Geno-type NDR [n (%)] PDR [n (%)] χ2 test Logistic regression analysis
P-value odds ratio
(95% CI)
Padjust-value
IL-10 rs1800896 T 95.85 90.71 TC 32 (8.29) 50 (16.03) 0.002 2.366 (1.144, 4.894) 0.020
   C 4.15 9.29 CC 0 (0) 4 (1.28) 0.026 1.524 (0) 0.999
      TT 354 (91.71) 258 (82.69) 0.001 Reference  
      Total 386 312    
VEGFA rs2010963 C 39.00 34.62 CG 214 (56.02) 140 (44.87) 0.003 0.588 (0.366, 0.946) 0.028
   G 60.99 65.38 CC 42 (10.99) 38 (12.18) 0.627 1.277 (0.578, 2.821) 0.546
      GG 126 (32.98) 134 (42.95) 0.007 Reference  
      Total 382 312    
RAGE rs2070600 C 72.80 82.00 CC 200 (51.81) 200 (66.67) 0.001 Reference  
   T 27.20 18.00 TT 24 (6.22) 8 (2.67) 0.029 0.180 (0.037, 0.872) 0.033
      CT 162 (41.97) 92 (30.67) 0.002 0.448 (0.266, 0.753) 0.002
      Total 386 300    
miR-146a rs2910164 C 63.68 65.88 CC 158 (41.58) 132 (44.59) 0.432  
   G 36.32 34.12 GG 54 (14.21) 38 (12.84) 0.606  
      CG 168 (44.21) 126 (42.57) 0.669  
      Total 380 296    
  1. Bold indicates statistically significant results
  2. Padjust values were adjusted for systolic blood pressure and using insulin treatment and glomerular filtration rate (GFR)