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Table 2 Cytokine profile (pg/mL, mean ± SD) and correlation between the concentration of cytokines and vascular endothelial growth factor (VEGF)

From: Aqueous humor cytokine levels through microarray analysis and a sub-analysis based on optical coherence tomography in wet age-related macular degeneration patients

  wAMD group (n = 13) Control group (n = 10) p* Correlation coefficient r p
IL-1α 40.54 ± 56.07 16.2 ± 11.88 0.278 0.46 0.028
IL-1β 7.6 ± 16.30 2.3 ± 3.69 0.734 0.76 0.001
IL-2 17.5 ± 12.99 11.6 ± 7.82 0.395 0.44 0.038
IL-4 10.3 ± 13.6 6.6 ± 4.04 0.962 0.56 0.009
IL-5 8.8 ± 7.99 9.2 ± 4.92 0.285 0.40 0.058
IL-6 24.4 ± 10.65 33.1 ± 11.19 0.095 0.64 0.002
IL-8 29.6 ± 32.62 19.1 ± 8.87 0.427 0.36 0.088
IL-10 2.6 ± 1.83 2.6 ± 1.06 0.792 0.70 0.001
IL-12p70 3.7 ± 4.77 2.3 ± 1.35 0.734 0.43 0.047
IL-13 9.3 ± 4.80 10.2 ± 2.72 0.193 0.52 0.014
GM-CSF 28.3 ± 12.98 33.6 ± 20.71 0.734 0.37 0.076
GRO 457.4 ± 215.28 381.1 ± 149.52 0.277 0.23 0.272
IFN-γ 293.1 ± 103.77 317.3 ± 114.59 0.651 0.21 0.329
MCP-1 951.8 ± 265.13 540.3 ± 261.01 0.003 −0.03 0.903
MIP-1α 679.1 ± 525.50 263.3 ± 226.85 0.041 −0.51 0.807
MIP-1β 32.9 ± 27.1 11.4 ± 10.1 0.034 0.29 0.180
MMP-9 151.4 ± 111.58 108.1 ± 79.15 0.343 0.18 0.393
RANTES 2.9 ± 3.76 0.9 ± 0.59 0.343 0.65 0.002
TNFα 977.0 ± 401.35 1140.8 ± 377.42 0.310 0.44 0.038
VEGF 236.2 ± 196.31 106.3 ± 30.41 0.009
  1. wAMD wet age-related macular degeneration
  2. *Mann-Whitney U test
  3. Spearman’s rank correlation