1st to 2nd | 2nd to 3rd | 3rd to 4th | 4th to 5th | 5th to 6th | 6th to 7th | 7th to 8th | |
---|---|---|---|---|---|---|---|
Interval-time between doses of antiangiogenic therapy (days), median (IQR) | 34 (28-61) | 33 (28-53) | 35 (21-90.5) | 28 (14-52) | 28 (14-61) | 30 (20-64) | 21.5 (14-28.75) |
Interval-time strata, N (%) | |||||||
< 20 days | 47 (7.5) | 37 (8.7) | 35 (22.2) | 27 (35) | 17 (45.9) | 5 (25.0) | 5 (41.7) |
20 – 40 days | 354 (57.1) | 239 (56.3) | 49 (31.0) | 26 (33.8) | 16 (43.2) | 8 (40.0) | 6 (50.0) |
40 – 60 days | 61 (9.8) | 56 (13.2) | 9 (5.7) | 6 (7.8) | 0 (0.0) | 1 (5.0) | 1 (8.4) |
60 – 80 days | 70 (11.2) | 34 (8.0) | 19 (12.0) | 10 (13.0) | 6 (16.2) | 4 (20.0) | 0 (0.0) |
80 – 100 days | 16 (2.5) | 14 (3.3) | 14 (8.9) | 2 (2.6) | 3 (8.1) | 0 (0.0) | 0 (0.0) |
> 100 days | 72 (11.6) | 44 (10.3) | 32 (20.2) | 6 (7.8) | 5 (13.5) | 2 (10.0) | 0 (0.0) |