All patients (n = 89) | Responsive group (n = 47) | Refractory group (n = 42) | P value | |
---|---|---|---|---|
Eye (OD : OS) | 49 : 40 | 26 : 21 | 23 : 19 | 0.958 |
Age | 62.5 ± 10.9 | 60.9 ± 11.7 | 64.2 ± 9.8 | 0.160 |
Sex (male : female) | 56 : 33 | 30 : 17 | 26 : 16 | 0.851 |
Follow-up duration (months) | 32.0 ± 21.8 | 30.0 ± 22.7 | 34.3 ± 20.8 | 0.348 |
Number of anti-VEGF injections in first year | 4.1 ± 2.3 | 2.4 ± 1.2 | 5.9 ± 1.6 | < 0.001 |
Baseline logMAR BCVA | 0.88 ± 0.56 | 0.84 ± 0.60 | 0.93 ± 0.52 | 0.416 |
LogMAR BCVA at 1 year | 0.60 ± 0.46 | 0.50 ± 0.49 | 0.72 ± 0.40 | 0.024 |
Pre-treatment CRT (μm) | 495 ± 175 | 451 ± 157 | 544 ± 183 | 0.011 |
Post-treatment best CRT (μm) | 253 ± 52 | 233 ± 33 | 275 ± 61 | < 0.001 |
CRT at 1 year (μm) | 329 ± 131 | 252 ± 38 | 414 ± 146 | < 0.001 |
Type of BRVO (major : macular) | 61 : 28 | 30 : 17 | 31 : 11 | 0.311 |
Type of macular edema on OCT | ||||
Cystoid macular edema (yes : no) | 47 : 42 | 21 : 26 | 26 : 16 | 0.104 |
Diffuse retinal thickening (yes : no) | 41 : 48 | 24 : 23 | 17 : 25 | 0.317 |
Serous retinal detachment (yes : no) | 13 : 76 | 6 : 41 | 7 : 35 | 0.603 |
Mean gray value over parafoveal region | 25.0 ± 21.1 | 14.1 ± 12.5 | 37.3 ± 22.1 | < 0.001 |
Mean gray value over perifoveal region | 23.3 ± 15.1 | 14.9 ± 8.9 | 32.7 ± 15.0 | < 0.001 |