Fig. 1
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12886-022-02275-4/MediaObjects/12886_2022_2275_Fig1_HTML.png)
There was no significant difference in OSDI score between the 2 groups before treatment. After treatment, the OSDI scores of both groups decreased (P < 0.001), and the OSDI score of the combination group was significantly lower than that of the monotherapy group (P < 0.001). *** indicates P < 0.001