Table 5 Comparison of IL-1, IL-6, and TNF-α levels between the 2 groups before and after treatment

Monotherapy group (n = 50)

47.28 ± 8.25

31.45 ± 5.08*

45.37 ± 6.38

29.73 ± 5.04*

53.26 ± 9.06

33.79 ± 6.58*

Combination group (n = 56)

49.53 ± 8.32

23.74 ± 5.21*

44.56 ± 6.12

20.55 ± 4.82*

54.57 ± 8.85

25.38 ± 6.14*

t

1.395

7.696

0.667

9.580

0.752

6.806

P value

0.166

< 0.001

0.506

< 0.001

0.454

< 0.001