Effect of anticoagulant/antiplatelet therapy on the development and progression of diabetic retinopathy

BMC Ophthalmology

Table 4 Overall PDR and DME events and HRs for PDR and DME measured for T2DM patients with diagnoses of NPDR during 5-year follow-up

	Anti-platelet/anti-coagulants
	No			Yes
Variables	Events n	PY	Rate^#	Events n	PY	Rate^#	Crude HR (95% CI)	Adjusted HR^† (95% CI)
PDR	13	16,146	0.81	4	4658	0.86	1.00 (0.32, 3.06)	0.85 (0.26, 2.77)
DME	21	16,132	1.30	4	4656	0.86	0.62 (0.21, 1.79)	0.65 (0.22, 1.94)

^#Incidence rate per 1000 person-years, DME Diabetic macular edema, HR Hazard ratio, PDR Proliferative diabetic retinopathy, PY Person-years.
^†Only confounding variables that were significant in the multivariable model were further analyzed.

ISSN: 1471-2415