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Table 4 Univariate and multivariable Cox regression analysis of risk factors for glaucoma-related adverse events in the group 2 and 3

From: Glaucoma and risk factors three years after congenital cataract surgery

Potential risk factors Univariate analysis Multivariable analysis
HR (95% CI) P-value HR (95% CI) P-value
Sex 0.803 (0.332–1.941) 0.626   
Age at surgery 0.979 (0.801–1.195) 0.833   
FHCC 4.461 (1.763–11.285) 0.002 50.463 (7.051–361.139)  < 0.001
History of prematurity 1.494 (0.493–4.521) 0.478   
PFV 1.489 (0.543–4.081) 0.439   
Pre-op AL 0.678 (0.479–0.959) 0.028 1.325 (0.750–2.341) 0.332
Pre-op CCT 1.013 (1.005–1.021) 0.002 1.021 (1.009–1.034) 0.001
Pre-op HCD 4.049 (2.105–7.752)  < 0.001 3.922 (1.558–9.804) 0.004
Pre-op ACD 0.126 (0.021–0.755) 0.023 0.256 (0.020–3.357) 0.300
Pre-op LT 3.559 (1.656–7.634) 0.001 3.745 (1.344–10.417) 0.012
Secondary IOL implantation 0.921 (0.321–2.641) 0.879   
  1. HR Hazard ratio, CI Confidence intervals, FHCC Family history of congenital cataract, PFV Persistent fetal vasculature, Pre-op Preoperative, AL Axial length, CCT Central corneal thickness, HCD Horizontal corneal diameter, ACD Anterior chamber depth, LT Lens thickness, IOL Intraocular lens