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Table 3 Medical treatment and outcome of treatment between patients with CMV-positive and CMV-negative Posner-Schlossman syndrome

From: Clinical characteristics of virus-related uveitic secondary glaucoma: focus on cytomegalovirus and varicella zoster virus

Characteristics

CMV-Negative

Patients (N = 22)

CMV-Positive

Patients (N = 25)

P Valuea

Medical treatment at the first visit

 Number of patients treated with antiglaucoma medication

20 (90.9)

15 (60)

.015*

 Number of antiglaucoma agents used simultaneously

2.0 (1.5–2.4)

1.0 (0.6–1.5)

.005*

 Frequency of corticosteroid eye drop (times per day)

2.5 (2.1–2.9)

2.8 (2.5–3.1)

.271

 Number of patients with corticosteroid dependency

13 (59.1)

12 (48)

.447

Ocular outcomes at the end of follow-up

 IOP (mm Hg)

16.7 (15.0–18.3)

14.4 (13.2–15.7)

.016*

 IOP reduction (mm Hg) (compared with the IOP at the first clinic visit)

13.0 (7.8–18.1)

14.6 (10.4–18.8)

.129

 mutton-fat KPs

9 (40.9)

15 (60)

.191

 Coin-shaped KPs

1 (4.5)

0 (0)

.281

 Tyndall effect

0 (0)

0 (0)

NA

Medical treatment at the end of follow-up

 Number of patients treated with antiglaucoma medication

11 (50)

8 (32)

.210

 Number of antiglaucoma agents used simultaneously

1.0 (0.5–1.5)

0.5 (0.2–0.9)

.148

 Frequency of corticosteroid eye drop (times per day)

0.5 (0.2–0.9)

1.0 (0.5–1.4)

.213

Duration of follow-up (weeks)

4.9 (3.8–6.0)

5.9 (4.7–7.2)

.202

  1. Data are expressed as mean (95% C.I) or number of patients (%)
  2. IOP intraocular pressure, KPs keratic precipitates, NA not applicable
  3. aχ2 test or Fisher’s exact test was used to compare proportions between CMV-negative and CMV-positive PSS; Mann-Whitney U test was used to compare continuous variables between CMV-negative and CMV-positive PSS
  4. *p < .05