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Table 2 Candidate independent PCA factors of metabolic control/tissue-injury

From: Multifocal pupillographic objective perimetry for assessment of early diabetic retinopathy and generalised diabetes-related tissue injury in persons with type 1 diabetes

PCA factor 1 (Metabolic)

PCA factor 2 (Tissue-injury)

PCA factor 3 (Lipid)

Variable

Correlation

Variable

Correlation

Variable

Correlation

BMI

− 0.73*

AGE

− 0.77*

Creatinine

0.77*

HbA1c 5-year

−0.65*

eGFR

0.76*

eGFR

−0.65*

HbA1c 2011

−0.65*

Biothesiometer

−0.68*

Cholesterol

−0.63*

Creatinine

−0.65*

Creatinine

−0.63*

LDL-chol

−0.62*

HbA1c test day

−0.62*

T1D duration

−0.59*

BMI

0.41

eGFR

0.61*

BMI

−0.44

T1D duration

−0.35

Triglycerides

−0.47

Triglycerides

−0.34

Potassium

−0.30

HDL-chol

0.43

Glucose

0.33

HbA1c on day

0.26

LDL-chol

0.40

Potassium

0.31

HDL-chol

−0.25

ETDRS

0.691*

 

0.554*

 

0.349

ETDRScen

0.678*

 

0.509*

 

0.455*

  1. Upper nine rows are correlation coefficients between the patient variables and the respective principal components analysis (PCA) factors. * indicates significant correlation (p < 0.02), bolding indicates the patient variables with the largest loadings for the respective PCA factor (i.e. the variable contributes more to that PCA factor than other PCA factors)
  2. Lower two rows are correlations between the two types of ETDRS scores and the respective PCA factors. * indicates significant correlation (p < 0.02)
  3. AGE advanced glycation end products
  4. Potassium and Glucose were the means for the two visits