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Table 1 Basic clinical data of subjects

From: Effects of intensive insulin therapy on the retinal microvasculature in patients with type 2 diabetes mellitus: a prospective observational study

Characteristics

Intensive Insulin (n = 36)

Oral Agent (n = 36)

P values

Age (years)

54.3 ± 5.8

55.5 ± 6.0

0.40*

Gender (M/F)

21/15

19/17

0.64†

Duration of diabetes (years)

3.5 ± 1.6

3.4 ± 1.9

0.78*

SBP (mmHg)

132.9 ± 12.8

134.1 ± 11.7

0.69*

DBP (mmHg)

84.8 ± 10.8

83.8 ± 8.7

0.68*

Hypertension

12 (33.3%)

15 (41.6%)

0.63+

FBG (mmol/L)

Pre-treatment

11.2 ± 1.9

10.8 ± 1.5

0.33*

At 1 M follow-up

5.6 ± 0.8

5.5 ± 0.9

0.65*

At 3 M follow-up

5.5 ± 0.9

6.0 ± 1.0

0.06*

At 6 M follow-up

5.4 ± 1.0

5.7 ± 0.9

0.17*

HbA1c (%)

Pre-treatment

9.7 ± 1.1

9.9 ± 1.1

0.60*

At 3 M follow-up

5.7 ± 0.8

6.0 ± 0.7

0.24*

At 6 M follow-up

6.0 ± 0.7

5.8 ± 0.6

0.25*

CREA (μmol/L)

67.9 ± 21.4

74.8 ± 21.4

0.18*

UREA (mmol/L)

5.5 ± 1.6

5.7 ± 1.8

0.52*

eGFR (ml/min)

105.9 ± 15.5

112.0 ± 12.4

0.07*

TG (mmol/L)

1.8 ± 0.8

1.6 ± 0.7

0.36*

CHOL (mmol/L)

5.3 ± 1.4

4.9 ± 1.1

0.11*

Hyperlipidemia

12 (33.3%)

8 (22.2%)

0.43†

Smoking

13 (36.1%)

10 (27.8%)

0.61†

  1. Data are shown as mean ± standard deviation
  2. *P values are from one-way ANOVA
  3. †P values are from Pearson Chi-square test
  4. SBP systolic blood pressure; DBP diastolic blood pressure; FBG fasting blood glucose; HbA1c glycated hemoglobulin; eGFR estimated glomerular filtration rate; CHOL Cholesterol; TG triglyceride; NPDR non-proliferative diabetic retinopathy